Chen Qimei (17 January 1878 – 18 May 1916) was a Chinese revolutionary activist and key figure of Green Gang, close political ally of Sun Yat-sen, and early mentor of Chiang Kai-shek. He was as one of the founders of the Republic of China, and the uncle of Chen Guofu and Chen Lifu.

In 1911, after the Wuchang Uprising, Chen's forces occupied Shanghai. He was then made military governor of the region. He fled to Japan with Sun Yat-sen upon the failure of the revolution against Yuan Shikai's dictatorship. They subsequently formed the Chinese Revolutionary Party, which later became the Kuomintang, or the Chinese Nationalist Party. As he was returning to Shanghai for another round of revolution, Yuan had him assassinated on May 18, 1916. The assassination was believed to have been carried out by Zhang Zongchang, a general loyal to Yuan.